Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
1. Choosing a job based on compensation alone
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
当芬兰程序员Jerry Jalava 2008年遇到车祸，他面临双重悲剧。首先，他失去了他的手指，对于靠打字生存的人来说是个大问题。其次，他必须跟一个幽默感过剩的医疗小组打交道。了解了他的遭遇后，一位外科医生竟然提议Jalava应该出门去买个“USB手指驱动器”。
5.3-D Printed Ears
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
As if 2016 hadn’t been hard enough for China’s workforce, an annual survey has revealed that more than half of the country’s white-collar employees got no year-end bonus ahead of the upcoming (and costly) lunar new year holiday.
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
BEST THROWING TOYS OUT OF PRAM
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Starbucks CEO Howard Schultz
Trends and targets in antiviral phototherapy
Negative emotions such as worrying, stress, depression and anger visit type D personalities more often. A small event that is usually overlooked by others can bother a type D a lot and even ruin his mood.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Nine out of the top 10 have all worked with Victoria's Secret in some capacity, with curve model Ashley being the only exception.
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Add your scores for 10 to 14 to find out how you score on the Social Inhibition scale.
Jacobs vowed at the meeting to improve management and cooperation with the association to enhance the credibility of the science. He stressed the publisher was not targeting China, as it had also retracted papers by experts from other countries, the statement said.
ACE2 as a potential therapeutic target for pandemic COVID-19
Diagnostic technologies for COVID-19: a review
7. Am I working too hard? Taking time to re-charge and spend time on activities that make you happy is so important. Honor your desire to pull back from work or school pressure when needed and give yourself time to breathe, even if it’s only for a few minutes at a time.
Capsized ship righted
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Stand: Costco CEO Craig Jelinek refused to open on Thanksgiving Day
7. “Out 1: Noli Me Tangere”(Jacques Rivette)
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
12. Scientists modify photosynthesis to boost crop yield
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Think you’ve had some bad job interviews this year? This survey is guaranteed tcheer you up (unless you happen tbe part of it). When staffing firm OfficeTeam asked 600 managers across North America tdescribe the most embarrassing interview blunders they had seen in 2014, here’s what they said.
Antiviral drug discovery: broad-spectrum drugs from nature
n. 卷轴，目录 v. 卷动
It is interpreted that in general, college education facilitates a long-term income advantage.
Influenza neuraminidase: A druggable target for natural products
Joseph Keller、Raymond Goldstein、Patrick Warren和Robin Ball获此殊荣，他们的研究课题是“人类马尾辫中头发的运动及受力平衡”。
Commodity-linked sectors have been especially hard hit in recent months. Mining-sector earnings tumbled 23 per cent last year. Oil and petrochemical refiners also saw profits slammed. Despite the fall in crude prices, many refiners remain subject to crude prices agreed to before the recent price drop, even as prices for their output fall.
Rounding out the top three is Chrissy Teigen, 31, who joins the list for the first time after raking in $13.5 million over the past 12 month-period.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
不错，2014年完全是一场灾难，只等着引爆。在《年内股市崩盘的概率有多大？》(Doomsday poll: 87% risk of stock crash by year-end)一文中，我们分析了今年年初以来的10大崩盘征兆。之后，我们又不断发现了更多新的妖魔。它们有如嘀嗒作响的定时炸弹，来自国会、最高法院、性问题、碳排放、石油巨头、国家安全局(NSA)、国税局(IRS)、茶党式财政紧缩。接踵而至，让人无法招架。
The role of biosensors in the detection of emerging infectious diseases
Included will be messages about smoking causing cancer and women who give the charmer a run for his money as 'little twists' have been added to make the story suitable for the modern reader.
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Total Program Cost: $181,500 in either Philadelphia or San Francisco
Will China's stock market climb back to the 6,000-point mark it reached two years ago? The stock market was at its most bullish back then, but if you ask the same question now, some would cite a global economy still reeling from a recession.
纽约前市长迈克尔·R·布隆伯格(Michael R. Bloomberg)正在为抗击气候变化花费自己私人财产的数千万美元，他在一份声明中说，“全球气温稳步上升、如今破纪录地上升的问题，不是一个未来的问题。这是一个迫在眉睫的明显危险，对经济、健康、环境和地缘政治有重大的危害。”
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
6. You dressed 10 times nicer than usual yesterday。
She created a whole world around the device -- one populated by humans, a whale in a top hat and dragons.
Inhibition of SARS coronavirus helicase by bismuth complexes
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
周边环境：这栋房屋坐落在摩德纳岛(Modena Island)，距萨凡纳市中心大约20英里（约32公里）。据该房源的代理人说，该社区设有门禁，在栎树丛与咸水湿地之间坐落着大约20栋房屋。摩德纳岛是斯基达韦岛(Skidaway Island)的一部分，岛上有一座由佐治亚大学的海洋学研究所和一座大型州立公园。
Then why do you go out and do the things you tell us not to do? 你们大人为什么去做与你们教导孩子相反的事情呢？
The study was based on 3,095 questionnaires from 2016 graduates and 1,661 questionnaires from employers across the country.
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
The piece was taken away for laboratory testing, and the Spielman family only received a phone call this month telling them the amulet had been identified.
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Indeed, last year produced the usual crop of new euphemisms for firing people. Infosys announced an “orderly ramp-down of about 3,000 persons”. Upworthy, a small media company, had the nerve to call sacking 14 people an “investment lay-off”. Otherwise, 2016 proved that the most egregious jargon is a sign not of failure, but of overexcitement.
Supporting Actress in a Mini-Series or Movie: Regina King, “American Crime”
"Premier Wen Jiabao's speech had a big focus on economic and social development. It's clear the government is working very hard to bring about the goal of building a prosperous society."
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
人力资源机构罗伯特?哈夫国际公司（Robert Half International）最近针对4,000名企业高管进行了一项调研。其中有88%的人预计，未来一年，公司的业务将有所好转。这不失为最鼓舞人心的消息了。
But the demagogue’s exploitation of such grievances threatens democracy.
Nineteen buildings disappeared in the space of 10 seconds after being demolished by a controlled explosion in China yesterday.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
'If that happens, that will need to be offset by some reduction of production out of Saudi [Arabia],' said Neil Gregson, a fund manager at J.P. Morgan Asset Management who oversees $3.5 billion in natural-resources investments.
Wang Jianlin, the entertainment mogul behind a series of high-profile acquisitions in Hollywood, and internet tycoon Jack Ma retained their spots at the top of the list, with fortunes of $32.1bn and $30.6bn respectively.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Yahoo CEO Marissa Mayer
The Harvard article suggests that protecting the brain with a heart-healthy diet could be the key to warding off dementia and keeping your memory intact well into your golden years. Some studies have suggested certain foods have a positive impact on memory, but no study thus far has revealed the existence of a miracle food. The idea that a heart-healthy diet could also prove beneficial to the brain and memory has become popular with doctors studying Alzheimer's disease and dementia. Some of the risk factors associated with heart disease are similar to those associated with dementia and Alzheimer's. Foods recommended for a heart-healthy diet include fruits, vegetables, and whole-grain bread, as well as beans, nuts, and olive oil. If you can't use every one of these 10 scientific secrets to a perfect memory, a healthy diet might help you avoid losing it!
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Four other domestic movies made it to the top ten list, among them are the third winner Never Say Die, Kung Fu Yoga in the fourth place, the fifth winner Journey to the West: The Demons Strike Back, and Youth in the eighth place.
More than 70% said self-realization was the biggest motivation to start a business.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
In 2013, the yuan appreciated almost 3% against the U.S. dollar, making 'Beijing a more expensive destination than in the past,' Jiang Yiyi noted.
Fans of Twilight will finally get to see how the wedding, honeymoon, and birth scenes play out with the release of Breaking Dawn Part 1. But before you catch R
来自5个不同国家的5所商学院今年首次进入排行榜。新加坡李光前商学院(Lee Kong Chian School of Business)是新进入者中排名最高的，直接跃居第36位。加拿大女王大学史密斯商学院(Queen’s Smith School of Business)的排名提高最大，跃升32位至第67名。
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
*最佳综艺导演：瑞安?麦克福(Ryan McFaul)，《艾米?舒莫的内心世界》(Inside Amy Schumer)
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
12. Is there something I am clinging to? We don’t always realize when we’re clinging to something harmful when it feels safe and familiar, whether it is an unfulfilling job, an unhealthy relationship, or a stagnant way of life. Recognize if you are clinging to something that isn’t serving you and work on taking small steps towards change and release.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
That Apple could launch a 2,000 yuan ($330) iPhone mini and be competitive with flagship products from Lenovo, Huawei, ZTE and Coolpad.
2013 Rank: 2
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
A modular microarray imaging system for highly specific COVID-19 antibody testing
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
China Everbright, the financial conglomerate that bought the Dah Sing Financial Centre for HK$10bn ($1.29bn), is just one of a number of mainland Chinese companies to have splashed out on headquarters in the city over the past year.
After being named Esquire's "Sexiest Women Alive" in October and Details' "Most F*ckable Celebrity" last month, the gorgeous 29-year-old has now snagged another honor: FHM's "Sexiest Woman In The World 2013," beating 99 other ladies and countless more who didn't even make the list.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Fantastic Beasts and Where to Find Them will be released worldwide on November 18, 2016.
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Meanwhile, celebrated American rapper Eminem proved to be the comeback king as he picked up the Best Hip Hop gong. The Lose Yourself hitmaker was up against the newer faces of hip hop, including Drake, Future, Kendrick Lamar and Post Malone.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Last but by no means least is our favourite fact that Norway once knighted a penguin. His name is Nils Olav, and he is a king penguin who now resides on Edinburgh Zoo, Scotland. He is the mascot and Colonel-in-Chief of the Norwegian Royal Guard. He was knighted on 15th August, 2008, which was approved by King Harald V, who stated during the ceremony that Nils was "in every way qualified to receive the honour and dignity of knighthood".
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
The sales volume peaks at around 15 million per day, with nearly 700 tickets sold in every second.
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
The 22-year-old Lawrence is the face of "The Hunger Games" franchise, and she may earn an Oscar nomination for her performance in "Silver Linings Playbook."
The government-sponsored students have signed an agreement that says they are required to reimburse the government if they do not return home after completing their studies, said Xiong Binqi, vice president of 21st Century Education Research Institute.
Usually things that go in the trash are of no value and don't need any kind of inspection, but QUBE wants to change that with "the world's first smart trash can." The QUBE claims to help you monitor your trash and help you recycle by using innovative technology.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
The paper quoted a number of students from the incoming class, who had a range of responses, including two who said it was the right approach to withdraw the offers. "I do not know how those offensive images could be defended," one student said.
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
IE商学院的在线MBA持续吸引着高素质的学员。其半数校友在入读时为高管级别，为所有上榜学院中比例最高的。该学院的在线MBA学员在毕业3年后的平均年薪最高，为17.9万美元，比薪资排第二位的（巴布森学院(Babson College)奥林商学院(Olin Business School)）高出约3万美元。
Roles With Bite
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Hitting the Top 100 for the first time, French fashion brand Dior and Silicon Valley automaker Tesla Motors Inc. were at Nos. 89 and 100 respectively.
Anti-HIV drug repurposing against SARS-CoV-2
Length-scale dependence of protein hydration-shell density
Others have come up with some, um, creative ways to say sayonara. When staffing firm OfficeTeam asked about 600 U.S. human resources managers to describe the weirdest ways they’ve seen or heard people resign lately, here’s what they said:
Wages will finally accelerate after years of stagnation
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
? Aid workers are worried about a food crisis in Haiti, where Hurricane Sandy killed 52 people last week. The UN is also concerned that flooding could lead to a sharp rise in cholera cases. At least 69 people were killed by Sandy in the Caribbean.
Curry scored 27 points and the defending champions moved within one victory of matching the best start in NBA history, holding off the Chicago Bulls 106-94 on Friday night to improve to 14-0.
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About 9.8 percent of the graduates are opting for "slow employment", meaning they will spend some time traveling, staying with their parents or waiting for opportunities to start up a business before figuring out their future plans, according to the survey.